Thioacetamide alters the regulation of cytidylyltransferase activity.


Using the weak hepatocarcinogen thioacetamide, we found a 73% decrease in microsomal CTP: Phosphocholine cytidylyltransferase (CT) activity after two months of treatment. We investigated the effect of different effectors on this enzyme activity. Results show that incubation of liver homogenates of treated animals in the presence of either oleate or spermine… (More)


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@article{Aylagas1993ThioacetamideAT, title={Thioacetamide alters the regulation of cytidylyltransferase activity.}, author={Hortensia Aylagas and Jes{\'u}s Osada and Carmen Cascales and Mar{\'i}a J Cascales and Maria Jes{\'u}s Mir{\~o}-Obradors and Evangelina Palacios-Alaiz}, journal={Biochemistry and molecular biology international}, year={1993}, volume={29 2}, pages={307-15} }