Thinking about flagellar oscillation.

  title={Thinking about flagellar oscillation.},
  author={Charles J. Brokaw},
  journal={Cell motility and the cytoskeleton},
  volume={66 8},
Bending of cilia and flagella results from sliding between the microtubular outer doublets, driven by dynein motor enzymes. This review reminds us that many questions remain to be answered before we can understand how dynein-driven sliding causes the oscillatory bending of cilia and flagella. Does oscillation require switching between two distinct, persistent modes of dynein activity? Only one mode, an active forward mode, has been characterized, but an alternative mode, either inactive or… CONTINUE READING

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