Think you know how miRNAs work? Think again.

  title={Think you know how miRNAs work? Think again.},
  author={Joel D. Richter},
  journal={Nature Structural &Molecular Biology},
VOLUME 15 NUMBER 4 APRIL 2008 NATURE STRUCTURAL & MOLECULAR BIOLOGY during DSB repair21. INO80 could also act behind the fork to stabilize or position nucleosomes assembled by histone chaperones and thus might counteract fork regression or back-up, which could ultimately lead to DSBs and genome instability1,2. Another possibility is that INO80 remodels nucleosomes behind the fork to expose sites for histone modifications that are in turn required for fork stabilization. One such modification… CONTINUE READING