Corpus ID: 217588574

Think beyond Prazosin When Treating Nightmares in PTSD

@article{Scarff2015ThinkBP,
  title={Think beyond Prazosin When Treating Nightmares in PTSD},
  author={Jonathan R. Scarff},
  journal={Current psychiatry},
  year={2015},
  volume={14},
  pages={56}
}
Nightmares are a common feature of posttraumatic stress disorder (PTSD) that could lead to fatigue, impaired concentration, and poor work performance. The [alpha]-1 antagonist prazosin decreases noradrenergic hyperactivity and reduces nightmares; however, it can cause adverse effects, be contraindicated, or provide no benefit to some patients. Consider these alternative medications to reduce nightmares in PTSD. Alpha-2 agonists Clonidine and guanfacine are [alpha]-2 agonists, used to treat… Expand
1 Citations

References

SHOWING 1-9 OF 9 REFERENCES
Gabapentin in PTSD: A Retrospective, Clinical Series of Adjunctive Therapy
  • M. Hamner, P. Brodrick, L. Labbate
  • Psychology, Medicine
  • Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
  • 2001
  • 121
Best practice guide for the treatment of nightmare disorder in adults.
  • R. Aurora, R. Zak, +9 authors T. Morgenthaler
  • Psychology, Medicine
  • Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
  • 2010
  • 221
  • PDF
No improvement of posttraumatic stress disorder symptoms with guanfacine treatment.
  • 86
  • PDF
Posttraumatic stress disorder and sleep difficulty.
  • 42
The suppression of nightmares with guanfacine.
  • 20
Cyproheptadine for recurrent nightmares.
  • H. Harsch
  • Psychology, Medicine
  • The American journal of psychiatry
  • 1986
  • 26