Corpus ID: 217588574

Think beyond Prazosin When Treating Nightmares in PTSD

  title={Think beyond Prazosin When Treating Nightmares in PTSD},
  author={Jonathan R. Scarff},
  journal={Current psychiatry},
Nightmares are a common feature of posttraumatic stress disorder (PTSD) that could lead to fatigue, impaired concentration, and poor work performance. The [alpha]-1 antagonist prazosin decreases noradrenergic hyperactivity and reduces nightmares; however, it can cause adverse effects, be contraindicated, or provide no benefit to some patients. Consider these alternative medications to reduce nightmares in PTSD. Alpha-2 agonists Clonidine and guanfacine are [alpha]-2 agonists, used to treat… Expand
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