Thin glomerular basement membrane disease: clinical significance of a morphological diagnosis--a collaborative study of the Italian Renal Immunopathology Group.

@article{Frasc2005ThinGB,
  title={Thin glomerular basement membrane disease: clinical significance of a morphological diagnosis--a collaborative study of the Italian Renal Immunopathology Group.},
  author={Giovanni Maria Frasc{\'a} and Andrea Onetti-Muda and Francesca Mari and Ilaria Longo and Elisa Scala and Chiara Pescucci and Dario Roccatello and Mirella Alpa and Rosanna Coppo and Giovanni Li Volti and S Feriozzi and Franco Bergesio and Francesco Paolo Schena and Alessandra Renieri},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2005},
  volume={20 3},
  pages={545-51}
}
BACKGROUND Thin glomerular basement membrane disease (TBMD) is a nephropathy defined by diffuse thinning of the glomerular basement membrane (GBM) at electron microscopy examination, without the alterations of Alport's syndrome (ATS). It is known that many patients with TBMD have a type IV collagen disorder and that the disease occasionally may be progressive. This study investigated 51 patients with the morphological diagnosis of TBMD lacking any sign of ATS, with the aim of defining the… CONTINUE READING

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