Thin and strong! The bioengineering dilemma in the structural and functional design of the blood-gas barrier.

@article{Maina2005ThinAS,
  title={Thin and strong! The bioengineering dilemma in the structural and functional design of the blood-gas barrier.},
  author={John Ndegwa Maina and John B West},
  journal={Physiological reviews},
  year={2005},
  volume={85 3},
  pages={
          811-44
        }
}
In gas exchangers, the tissue barrier, the partition that separates the respiratory media (water/air and hemolymph/blood), is exceptional for its remarkable thinness, striking strength, and vast surface area. These properties formed to meet conflicting roles: thinness was essential for efficient flux of oxygen by passive diffusion, and strength was crucial for maintaining structural integrity. What we have designated as "three-ply" or "laminated tripartite" architecture of the barrier appeared… 

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...

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