Thimerosal induces oxidative stress in HeLa S epithelial cells.

  title={Thimerosal induces oxidative stress in HeLa S epithelial cells.},
  author={Seunghwan Lee and Md Firoz Mian and H Lee and Chung-Boo Kang and J Kim and Sung Ho Ryu and Pann Ghill Suh and Euikyung Kim},
  journal={Environmental toxicology and pharmacology},
  volume={22 2},
Thimerosal is one of the most widely used preservatives and is found in a variety of biological products, including vaccines, contact lens cleaning solutions, and cosmetics. It has been reported to have harmful effects on epithelial tissues, such as causing conjunctivitis or contact dermatitis. However, the molecular mechanism of its toxicity has not been characterized using epithelial tissues. In the present study, we report that reactive oxygen species play a key role in thimerosal-induced… CONTINUE READING
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