Thicker posterior insula is associated with disease duration in women with irritable bowel syndrome (IBS) whereas thicker orbitofrontal cortex predicts reduced pain inhibition in both IBS patients and controls.

@article{Pich2013ThickerPI,
  title={Thicker posterior insula is associated with disease duration in women with irritable bowel syndrome (IBS) whereas thicker orbitofrontal cortex predicts reduced pain inhibition in both IBS patients and controls.},
  author={Mathieu Pich{\'e} and J Chen and Mathieu Roy and Pierre Poitras and Mickael Bouin and Pierre Rainville},
  journal={The journal of pain : official journal of the American Pain Society},
  year={2013},
  volume={14 10},
  pages={1217-26}
}
UNLABELLED Patients with irritable bowel syndrome (IBS) are affected by chronic abdominal pain and show decreased pain inhibition. Moreover, they exhibit differences in brain morphology compared with healthy volunteers. The aim of this study was to examine whether decreased pain inhibition is associated with altered brain morphology in IBS patients. Structural magnetic resonance imaging scans were acquired in 14 female patients with diarrhea-predominant IBS and 14 controls. Pain and anxiety… CONTINUE READING
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