Thick-section fluorescence in situ hybridization on formalin-fixed, paraffin-embedded archival tissue provides a histogenetic profile.

Abstract

Fluorescence in situ hybridization has become a major tool for analysis of gene and chromosome copy number in normal and malignant tissue. The technique has been applied widely to fresh tissue and dispersed formalin-fixed, paraffin-embedded archival tissue, but its use on sections of archival tissue has largely been limited to sections < 6 mu thick. This… (More)

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@article{Thompson1994ThicksectionFI, title={Thick-section fluorescence in situ hybridization on formalin-fixed, paraffin-embedded archival tissue provides a histogenetic profile.}, author={Christopher J. Thompson and Philip E Leboit and P. M. Nederlof and J. W. Gray}, journal={The American journal of pathology}, year={1994}, volume={144 2}, pages={237-43} }