Thiazolidinediones stimulate uncoupling protein-2 expression in cell lines representing white and brown adipose tissues and skeletal muscle.

Abstract

Thiazolidinediones (TZD) are PPAR gamma ligands that sensitize tissues to insulin. A cDNA encoding a mitochondrial protein likely to act as uncoupler (uncoupling protein 2, UCP2) has been recently cloned. Since TZD have been reported to increase energy expenditure in animals, we have examined the effects of these drugs on the expression of UCP2 mRNA in cell… (More)
DOI: 10.1210/endo.139.1.5808

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Cite this paper

@article{Camirand1998ThiazolidinedionesSU, title={Thiazolidinediones stimulate uncoupling protein-2 expression in cell lines representing white and brown adipose tissues and skeletal muscle.}, author={Anne Camirand and V{\'e}ronique Marie and Roge Rio Rabelo and Jorge Enrique Silva}, journal={Endocrinology}, year={1998}, volume={139 1}, pages={428-431} }