Thiazolidinediones plus metformin association on body weight in patients with type 2 diabetes.

@article{Derosa2011ThiazolidinedionesPM,
  title={Thiazolidinediones plus metformin association on body weight in patients with type 2 diabetes.},
  author={Giuseppe Derosa and Pamela Maffioli},
  journal={Diabetes research and clinical practice},
  year={2011},
  volume={91 3},
  pages={
          265-70
        }
}
There are different studies about the efficacy and safety and tolerability of thiazolidinediones added to metformin. The reported improved glycemic control with thiazolidinediones use seems to be associated with an increase in weight with an estimated 2-3 kg weight gain suggesting that maybe thiazolidinediones are not safe for the clinical use. Other authors reported that thiazolidinediones give an improvement in the glycemic without giving weight gain. With our review, we want to evaluate the… CONTINUE READING
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