Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus.

@article{Habib2010ThiazolidinedioneUA,
  title={Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus.},
  author={Zeina A Habib and Suzanne L. Havstad and Karen J Wells and George W. Divine and Manel Pladevall and L. Keoki Williams},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2010},
  volume={95 2},
  pages={592-600}
}
CONTEXT Thiazolidinedione (TZD) use has recently been associated with an increased risk of fractures. OBJECTIVE The aim of this study was to determine the time-dependent relationship between TZD use and fracture risk. DESIGN We conducted a retrospective cohort study in a large health system in southeast Michigan. PATIENTS PATIENTS who received care from the health system were included if they were at least 18 yr of age, had a diagnosis of diabetes, and had at least one prescription for an… CONTINUE READING

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