Thiazolidinedione-induced congestive heart failure.

  title={Thiazolidinedione-induced congestive heart failure.},
  author={Alice Cheng and Ivan George Fantus},
  journal={The Annals of pharmacotherapy},
  volume={38 5},
OBJECTIVE To report 2 cases of thiazolidinedione (TZD)-associated congestive heart failure (CHF). As of March 13, 2004, one of the cases may represent the first description of TZD-associated cardiomyopathy in humans. case summaries: A 57-year-old obese white man with type 2 diabetes was treated with pioglitazone 30 mg/day and insulin. He had no prior history of CHF and had an excellent exercise tolerance. Over the first 4 weeks of pioglitazone therapy, the patient experienced significant weight… CONTINUE READING