Thiazolidinedione derivatives in diabetes and cardiovascular disease: an update.

@article{Sarafidis2008ThiazolidinedioneDI,
  title={Thiazolidinedione derivatives in diabetes and cardiovascular disease: an update.},
  author={Pantelis A Sarafidis},
  journal={Fundamental & clinical pharmacology},
  year={2008},
  volume={22 3},
  pages={
          247-64
        }
}
As the incidence and the public health impact of type 2 diabetes are constantly rising, treatment of hyperglycemia, prevention of diabetes-related complications are currently top medical priorities. Within the last decade several new classes of oral hypoglycemic agents were added to our armamentarium against diabetes. Among these new classes, the group of thiazolidinediones, which act through reduction of insulin resistance is perhaps the most widely used. For about 20 years, numerous… CONTINUE READING

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