Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation.


As part of ongoing studies in developing new antimicrobials, we report the synthesis of a new class of structurally novel derivatives, that incorporate two known bioactive structures a thiazole and chalcone, to yield a class of compounds with interesting antimicrobial properties. Evaluation of antibacterial activity showed that almost all the compounds… (More)
DOI: 10.1016/j.bmc.2011.04.007


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