Thiazide diuretics and the risk of hip fracture.
@article{Aung2011ThiazideDA, title={Thiazide diuretics and the risk of hip fracture.}, author={Koko Aung and T. Htay}, journal={The Cochrane database of systematic reviews}, year={2011}, volume={10}, pages={ CD005185 } }
BACKGROUND
Thiazide diuretics are one of the most commonly prescribed antihypertensive agents worldwide. Thiazides reduce urinary calcium excretion. Chronic ingestion of thiazides is associated with higher bone mineral density. It has been suggested that thiazides may prevent hip fracture. However, there are concerns that diuretics, by increasing the risk of fall in elderly, could potentially negate its beneficial effects on hip fracture.
OBJECTIVES
To assess any association between the use… CONTINUE READING
Figures, Tables, and Topics from this paper
67 Citations
Thiazide diuretics and risk of hip fracture: A Bayesian meta-analysis of cohort studies
- Medicine
- 2020
- 1
Thiazide diuretic usage and risk of fracture: a meta-analysis of cohort studies
- Medicine
- Osteoporosis International
- 2018
- 12
- Highly Influenced
The Impact of Antihypertensive Medications on Bone Mineral Density and Fracture Risk
- Medicine
- Current Cardiology Reports
- 2017
- 19
Association of 3 Different Antihypertensive Medications With Hip and Pelvic Fracture Risk in Older Adults: Secondary Analysis of a Randomized Clinical Trial
- Medicine
- JAMA internal medicine
- 2017
- 33
- PDF
Response to: A role for thiazide diuretic therapy in preventing bone loss, fracture and nephrolithiasis in individuals with thalassemia and hypercalciuria?
- Medicine
- Osteoporosis International
- 2017
Optimal age of commencing and discontinuing thiazide therapy to protect against fractures
- Medicine
- Osteoporosis International
- 2015
- 3
Furosemide Increases the Risk of Hyperparathyroidism in Chronic Kidney Disease
- Medicine
- American Journal of Nephrology
- 2016
- 7
Diuretic-induced hyponatremia and osteoporotic fractures in patients admitted to the emergency department.
- Medicine
- Maturitas
- 2013
- 29
ACE inhibitors and the risk of fractures: a meta-analysis of observational studies
- Medicine
- Endocrine
- 2016
- 7
References
SHOWING 1-10 OF 78 REFERENCES
Thiazide diuretic agents and the incidence of hip fracture.
- Medicine
- The New England journal of medicine
- 1990
- 202
Thiazide diuretics and the risk of hip fracture. Results from the Framingham Study.
- Medicine
- JAMA
- 1991
- 96
Thiazide diuretics and fractures: Can meta‐analysis help?
- Medicine
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- 1995
- 127
Current use of thiazide diuretics and prevention of femur fractures.
- Medicine
- Journal of clinical epidemiology
- 1996
- 82
- PDF
Effects of Thiazide Diuretic Therapy on Bone Mass, Fractures, and Falls
- Medicine
- Annals of Internal Medicine
- 1993
- 154