Thiamine and zinc in prevention or therapy of lead intoxication.

  title={Thiamine and zinc in prevention or therapy of lead intoxication.},
  author={Swaran J. S. Flora and Surendra Singh and Sushil Kumar Tandon},
  journal={The Journal of international medical research},
  volume={17 1},
Thiamine, zinc or their combination given through gastric gavage were investigated for their ability to prevent or treat experimental lead toxicity in rats. Simultaneous dietary supplementation with thiamine plus zinc was found to be the most effective way of reducing the lead-induced inhibition of delta-aminolevulinic acid dehydratase activity in blood, urinary, excretion of delta-aminolevulinic acid and accumulation of lead in blood, liver and kidney. Prevention was more effective than post… CONTINUE READING
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