Thiamine and benfotiamine counteract ultrasound-induced aggression, normalize AMPA receptor expression and plasticity markers, and reduce oxidative stress in mice

@article{Gorlova2019ThiamineAB,
  title={Thiamine and benfotiamine counteract ultrasound-induced aggression, normalize AMPA receptor expression and plasticity markers, and reduce oxidative stress in mice},
  author={Anna Gorlova and Dmitrii Pavlov and Daniel C. Anthony and Eugene D Ponomarev and Margaux Sambon and Andrey T Proshin and Igor Shafarevich and Diana Babaevskaya and Klaus-Peter Lesсh and Lucien Bettendorff and Tatyana Strekalova},
  journal={Neuropharmacology},
  year={2019},
  volume={156}
}
The negative societal impacts associated with the increasing prevalence of violence and aggression is increasing, and, with this rise, is the need to understand the molecular and cellular changes that underpin ultrasound-induced aggressive behavior. In mice, stress-induced aggression is known to alter AMPA receptor subunit expression, plasticity markers, and oxidative stress within the brain. Here, we induced aggression in BALB/c mice using chronic ultrasound exposure and examined the impact of… Expand

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