2,859 Citations
Self-generated theta oscillations in the hippocampus
- Biology, PsychologyNature Neuroscience
- 2009
The results suggest that CA1 theta rhythm can emerge from the coupling of multiple autonomous hippocampal theta oscillators, and this work finds several intrinsic, atropine-resistant theta generators in CA1.
Neural circuits underlying the generation of theta oscillations
- BiologyJournal of Physiology-Paris
- 2012
Interneuronal mechanisms of hippocampal theta oscillation in full-scale model of the CA1 circuit
- BiologybioRxiv
- 2016
A data-driven, supercomputer-based, full-scale (1:1) model of the CA1 area was developed and its interneurons were studied to reveal new insights into the spatiotemporal organization of theCA1 circuit during theta oscillations.
Interaction between neocortical and hippocampal networks via slow oscillations.
- BiologyThalamus & related systems
- 2005
It is suggested that slow oscillation of the neocortex, which was discovered by Mircea Steriade, temporally coordinates the self-organized oscillations in the neoc cortex, entorhinal cortex, subiculum and hippocampus.
Behavior-Dependent Coordination of Multiple Theta Dipoles in the Hippocampus
- Biology, PsychologyThe Journal of Neuroscience
- 2009
The findings reveal a consortium of layer-specific theta dipoles (current sinks and sources) generated by the rhythmic flow of ions into and out of hippocampal cells and suggest that these different theta generators flexibly coordinate hippocampal regions and layers to support behavioral task performance.
Interneuronal mechanisms of hippocampal theta oscillations in a full-scale model of the rodent CA1 circuit
- BiologyeLife
- 2016
A data-driven, supercomputer-based, full-scale (1:1) model of the rodent CA1 area is developed and its interneurons are studied during theta oscillations to reveal new insights into the spatiotemporal organization of the CA1 circuit during theTA oscillations.
Synchronization of neural oscillations as a possible mechanism underlying episodic memory: a study of theta rhythm in the hippocampus.
- Biology, PsychologyJournal of integrative neuroscience
- 2004
An autoassociative network model of the hippocampus and the entorhinal cortex was analyzed to explore mechanisms underlying episodic memory and suggests a possible role of theta oscillations in memory encoding and online processing of episodic events.
Phase relations of theta oscillations in a computer model of the hippocampal CA1 field: Key role of Schaffer collaterals
- BiologyNeural Networks
- 2019
The Theta Rhythm of the Hippocampus: From Neuronal and Circuit Mechanisms to Behavior
- Biology, PsychologyFrontiers in Cellular Neuroscience
- 2021
This review focuses on the neuronal and circuit mechanisms involved in the generation of the theta (θ) rhythm and of its participation in behavior and discusses that the loss of this interaction is at the base of various neurophatological conditions.
References
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Inhibitory CA1-CA3-hilar region feedback in the hippocampus.
- BiologyScience
- 1994
A longitudinally widespread, inhibitory feedback in rat brain from the CA1 area to the CA3 and hilar regions was observed, and this long-range, cross-regional inhibition may allow precise synchronization of population activity by timing the occurrence of action potentials in the principal cells.
Intrinsic oscillations in CA3 hippocampal pyramids: Physiological relevance to theta rhythm generation
- BiologyHippocampus
- 1998
It is shown that hippocampal neurons, recorded from juvenile and adult slices, are endowed with intrinsic properties that allow the generation of a steady oscillatory activity, and regularly occurring membrane potential oscillations can be detected since postnatal day 10 and their frequency increases with age, i.e., during the following 2 weeks.
Pacemaker neurons for the theta rhythm and their synchronization in the septohippocampal reciprocal loop.
- BiologyJournal of neurophysiology
- 2002
Hippocampal theta (4-10 Hz) oscillation represents a well-known brain rhythm implicated in spatial cognition and memory processes. Its cellular mechanisms remain a matter of debate, and previous…
Do septal neurons pace the hippocampal theta rhythm?
- Biology, PsychologyTrends in Neurosciences
- 1990
Oscillatory and Intermittent Synchrony in the Hippocampus: Relevance to Memory Trace Formation
- Biology
- 1994
This field potential reflects summated EPSPs in the apical dendrites of CA1 pyramidal neurons as a result of population synchrony in the CA3 recurrent network.
Theta in hippocampal slices: Relation to synaptic responses of dentate neurons
- BiologyBrain Research Bulletin
- 1987
Intracellular correlates of hippocampal theta rhythm in identified pyramidal cells, granule cells, and basket cells
- BiologyHippocampus
- 1995
Observations suggest that dendritic currents underlying theta in the awake rat may not be revealed under urethane anesthesia, and cellular‐synaptic generation of rhythmic slow activity in the hippocampus is investigated by intracellular recording from principal cells and basket cells in anesthetized rats.
GABAergic modulation of hippocampal population activity: sequence learning, place field development, and the phase precession effect.
- BiologyJournal of neurophysiology
- 1997
A detailed biophysical model of hippocampal region CA3 was constructed to study how GABAergic modulation influences place field development and the learning and recall of sequence information and found periodic GABA(B)-receptor-mediated suppression of excitatory and inhibitory transmission at intrinsic but not afferent fibers resulted in sensory information about location being dominant during early portions of each theta cycle.
Expression, control, and probable functional significance of the neuronal theta-rhythm
- BiologyProgress in Neurobiology
- 1995
Intracellular records of carbachol-induced theta rhythm in hippocampal slices
- BiologyBrain Research
- 1988