Thermotolerance and intracellular pH in two Chinese hamster cell lines adapted to growth at low pH.

Abstract

As an in vitro model for the low extracellular pH (pHe) which has frequently been observed in tumors, cell lines have been grown in a low-pH medium in order to allow cell adaptation to that milieu. Two Chinese hamster cell lines [Chinese hamster ovary (CHO) and Chinese hamster ovarian carcinoma (OvCa)] were compared, both of which acquired thermotolerance… (More)

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@article{Wahl1996ThermotoleranceAI, title={Thermotolerance and intracellular pH in two Chinese hamster cell lines adapted to growth at low pH.}, author={Mark Wahl and Ronald Allen Coss and Suzanne B. Bobyock and Donna Leeper and Christien Owen}, journal={Journal of cellular physiology}, year={1996}, volume={166 2}, pages={438-45} }