Thermostable (SULT1A1) and thermolabile (SULT1A3) phenol sulfotransferases in human osteosarcoma and osteoblast cells.

@article{Dubin2001ThermostableA,
  title={Thermostable (SULT1A1) and thermolabile (SULT1A3) phenol sulfotransferases in human osteosarcoma and osteoblast cells.},
  author={R L Dubin and Candice M Hall and C L Pileri and Patrick E. Kudlacek and Xian Yu Li and John A. Yee and Mark L. Johnson and Robert B J Anderson},
  journal={Bone},
  year={2001},
  volume={28 6},
  pages={617-24}
}
Sulfate conjugation is an important pathway in the metabolism of many drugs, xenobiotic compounds, and hormones. Sulfotransferases (SULTs) catalyze these reactions and have been detected and characterized in various human tissues including the liver and small intestine. Substrates for SULTs that include estrogen and thyroid hormones have well-established roles affecting skeletal integrity and disease processes. We performed the following studies to determine the presence of SULTs in human… CONTINUE READING