Thermostability profile of Newcastle disease virus (strain I–2) following serial passages without heat selection

@article{Wambura2006ThermostabilityPO,
  title={Thermostability profile of Newcastle disease virus (strain I–2) following serial passages without heat selection},
  author={Philemon Nyangi Wambura and Joanne Meers and Peter B Spradbrow},
  journal={Tropical Animal Health and Production},
  year={2006},
  volume={38},
  pages={527-531}
}
I–2 is an avirulent strain of Newcastle disease virus. During establishment of the I-2 strain master vaccine seed, a series of selection procedures was carried out at 56°C in order to enhance heat resistance. This master seed is used to produce a working seed, which is then employed to produce the vaccine. These two passages are done without further heat selection; however, it is not known how rapidly and to what extent thermostable variants would be lost during further passage. The study was… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 13 references

Newcastle disease

  • D. J. Alexander
  • 1998
1 Excerpt

A review of the use of food carriers for the delivery of oral Newcastle disease vaccine

  • P. B. Spradbrow, S. E. Grimes
  • 1992

Newcastle disease diagnosis

  • D. J. Alexander
  • Newcastle Disease, (Kluwer,
  • 1988
2 Excerpts

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