Thermostability and reversibility of silver nanoparticle-protein binding.

@article{Wang2015ThermostabilityAR,
  title={Thermostability and reversibility of silver nanoparticle-protein binding.},
  author={Bo Wang and Shane A. Seabrook and Praveen Nedumpully-Govindan and Pengyu Chen and Hong Yin and Lynne J. Waddington and Vidana Chandana Epa and David A. Winkler and Jason K. Kirby and Feng Ding and Pu Chun Ke},
  journal={Physical chemistry chemical physics : PCCP},
  year={2015},
  volume={17 3},
  pages={
          1728-39
        }
}
The interactions between nanoparticles (NPs) and proteins in living systems are a precursor to the formation of a NP-protein "corona" that underlies cellular and organism responses to nanomaterials. However, the thermodynamic properties and reversibility of NP-protein interactions have rarely been examined. Using an automated, high-throughput and temperature-controlled dynamic light scattering (DLS) technique we observed a distinct hysteresis in the hydrodynamic radius of branched… 
View on PubMed
dlab.clemson.edu
25 Citations
Background Citations
1
Methods Citations
1
Results Citations
1

Figures and Tables from this paper

25 Citations

Citation Type

Citation Type

Probing the modulated formation of gold nanoparticles-beta-lactoglobulin corona complexes and their applications.
TLDR
The superior stability of the corona led us to further explore its biomedical applications, such as in the smartphone-based point-of-care biosensing of Escherichia coli and in the computed tomography of the gastrointestinal tract through oral administration to probe GI tolerance and functions.
Promising insights into the kosmotropic effect of magnetic nanoparticles on proteins: The pivotal role of protein corona formation
TLDR
An integrated picture of protein–MNP interaction is provided that affinity of proteins for MNPs is strongly affected by the similarity of protein and MNP surface charges, and thermal stability is influenced to a higher extent in more strongly bound proteins.
Molecular Modeling of Protein Corona Formation and Its Interactions with Nanoparticles and Cell Membranes for Nanomedicine Applications
TLDR
MD simulations have uncovered the mechanism regarding the competitive adsorption and desorption of plasma proteins, which helps to explain the Vroman effect and indicate that simulations can now provide predications in excellent agreement with experimental observations as well as atomic-scale insights into protein corona formation and interactions.
Probing the binding behavior and kinetics of silver nanoparticles with bovine serum albumin
Nanomaterials have been utilized as multifunctional diagnostic and therapeutic agents. However, the effective application of nanomaterials is hampered by our limited understanding and control over…
Understanding the graphene quantum dots-ubiquitin interaction by identifying the interaction sites
Cofibrillization of Pathogenic and Functional Amyloid Proteins with Gold Nanoparticles against Amyloidogenesis.
TLDR
A facile scheme of cofibrillizing pathogenic and functional amyloid fibrils via gold nanoparticles (AuNPs) and their applications against amyloidalogenesis is shown, for the first time, and has implications for understanding the in vivo cross-talk between amyloids of different pathologies.
Experimental and molecular docking study of the binding interactions between bovine α-lactalbumin and oleuropein
Biological and environmental surface interactions of nanomaterials: characterization, modeling, and prediction.
  • Ran Chen, J. Riviere
  • Biology, Chemistry
    Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
  • 2017
TLDR
To quantitatively decipher these physicochemical surface interactions, computational methods can be used for either analyses of large amounts of experimental characterization data, or theoretical prediction of the interactions, and consequent biological behavior in the body after administration.
Surface modification of alumina-coated silica nanoparticles in aqueous sols with phosphonic acids and impact on nanoparticle interactions.
TLDR
Surface modification of aqueous sols with PAs allows for the grafting of a higher density and a wider variety of organic groups than organosilanes, offering an increased control of the interactions between NPs, which is of interest for designing waterborne nanocomposites.
Nanosilver Mitigates Biofilm Formation via FapC Amyloidosis Inhibition.
TLDR
This study demonstrates the antimicrobial potential of safe nanotechnology through the novel route of amyloidosis inhibition through silver nanoparticles and nanoclusters capped with cationic branched polyethylenimine polymer at concentrations safe to mammalian cells.
...
1
2
3
...

References

SHOWING 1-10 OF 41 REFERENCES
Contrasting Effects of Nanoparticle Binding on Protein Denaturation
TLDR
Examination of protein denaturation in the presence of NPs revealed a greatly elevated cytokine production in the cells treated with fullerol-lysozyme and a mostly unchanged TNF-α secretion in THP-1 cells exp...
Docking of ubiquitin to gold nanoparticles.
TLDR
The results provide a model of the ensemble of structures constituting the ubiquitin-gold surface complex, and insights into the driving forces for the binding of Ubiquitin to gold nanoparticles, the role of nanoparticle surfactants (citrate) in the association process, and the origin of the perturbations in the NMR chemical shifts.
Direct observation of a single nanoparticle-ubiquitin corona formation.
TLDR
The atomic and molecular details of the structural and dynamic characteristics of nanoparticle-protein corona formation are revealed, including an unusual stretched-exponential behavior and a rich binding kinetics.
Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
TLDR
The long-lived (“hard”) protein corona formed from human plasma is studied for a range of nanoparticles that differ in surface properties and size and both size and surface properties were found to play a very significant role.
Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles
TLDR
The rates of protein association and dissociation are determined using surface plasmon resonance technology with nanoparticles that are thiol-linked to gold, and through size exclusion chromatography of protein–nanoparticle mixtures, and this method is developed into a systematic methodology to isolate nanoparticle-associated proteins.
Effect of fullerenol surface chemistry on nanoparticle binding-induced protein misfolding.
TLDR
Overall, the results revealed a distinct role of surface chemistry on nanoparticle-protein binding and binding-induced protein misfolding.
Understanding biophysicochemical interactions at the nano-bio interface.
TLDR
Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
Temperature: the "ignored" factor at the NanoBio interface.
TLDR
The results indicate that the degree of protein coverage and the composition of the adsorbed proteins on the NPs' surface depend on the temperature at which the protein corona is formed, and the uptake of NPs is affected by the temperature.
Protein-nanoparticle interactions
Synthesis of positively charged silver nanoparticles via photoreduction of AgNO3 in branched polyethyleneimine/HEPES solutions.
TLDR
Positive charged silver nanoparticles demonstrate superior SERS activity over negatively charged citrate reduced Ag nanoparticles for the detection of thiocyanate and perchlorate ions and are promising candidates for sensing and detection of a variety of negatively charged analytes in aqueous solutions using surface-enhanced Raman spectroscopy (SERS).
...
1
2
3
4
5
...