Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK.

Abstract

TREK-1, TREK-2 and TRAAK are members of the two-pore domain K+ (K2P) channel family and are activated by membrane stretch and free fatty acids. TREK-1 has been shown to be sensitive to temperature in expression systems. We studied the temperature-sensitivity of TREK-2 and TRAAK in COS-7 cells and in neuronal cells. In transfected COS-7 cells, TREK-2 and… (More)

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@article{Kang2005ThermosensitivityOT, title={Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK.}, author={Dawon Kang and Changyong Choe and Donghee Kim}, journal={The Journal of physiology}, year={2005}, volume={564 Pt 1}, pages={103-16} }