Thermoresponsive Nanoparticles of Self-Assembled Block Copolymers as Potential Carriers for Drug Delivery and Diagnostics.

@article{Rahikkala2015ThermoresponsiveNO,
  title={Thermoresponsive Nanoparticles of Self-Assembled Block Copolymers as Potential Carriers for Drug Delivery and Diagnostics.},
  author={Antti Rahikkala and Vladimir O Aseyev and Heikki J Tenhu and Esko I. Kauppinen and Janne Raula},
  journal={Biomacromolecules},
  year={2015},
  volume={16 9},
  pages={2750-6}
}
Thermally responsive hydrogel nanoparticles composed of self-assembled polystyrene-b-poly(N-isopropylacrylamide)-b-polystyrene block copolymers and fluorescent probe 1-anilinonaphthalene-8-sulfonic acid have been prepared by aerosol flow reactor method. We aimed exploring the relationship of intraparticle morphologies, that were, PS spheres and gyroids embedded in PNIPAm matrix, as well PS-PNIPAm lamellar structure, to probe release in aqueous solution below and above the cloud point… CONTINUE READING

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