Thermodynamics of the pseudo-knot in helix 18 of 16S ribosomal RNA.

Abstract

A fragment of E. coli 16S rRNA formed by nucleotides 500 to 545 is termed helix 18. Nucleotides 505-507 and 524-526 form a pseudo-knot and its distortion affects ribosome function. Helix 18 isolated from the ribosome context is thus an interesting fragment to investigate the structural properties and folding of RNA with pseudo-knots. With all-atom molecular… (More)
DOI: 10.1002/bip.23116

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