Thermodynamics of target peptide recognition by calmodulin and a calmodulin analogue: implications for the role of the central linker.

Abstract

The thermodynamics of interaction of two model peptides melittin and mastoparan with bovine brain calmodulin (CAM) and a smaller CAM analogue, a calcium binding protein from Entamoeba histolytica (CaBP) in 10 mM MOPS buffer (pH 7.0) was examined using isothermal titration calorimetry (ITC). These data show that CAM binds to both the peptides and the… (More)

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@article{Moorthy1999ThermodynamicsOT, title={Thermodynamics of target peptide recognition by calmodulin and a calmodulin analogue: implications for the role of the central linker.}, author={Anitha K Moorthy and Balasubramanian Gopal and Posettihalli R. Satish and Sujit Bhattacharya and Arunabh Bhattacharya and Mathur R. N. Murthy and Avadhesha Surolia}, journal={FEBS letters}, year={1999}, volume={461 1-2}, pages={19-24} }