Thermodynamics of internal C.T mismatches in DNA.

@article{Allawi1998ThermodynamicsOI,
  title={Thermodynamics of internal C.T mismatches in DNA.},
  author={H T Allawi and J. SantaLucia},
  journal={Nucleic acids research},
  year={1998},
  volume={26 11},
  pages={2694-701}
}
Thermodynamics of 23 oligonucleotides with internal single C.T mismatches were obtained by measuring UV absorbance as a function of temperature. Results from these 23 duplexes were combined with three measurements from the literature to derive nearest-neighbor thermodynamic parameters for seven linearly independent trimer sequences with internal C.T mismatches. The data show that the nearest-neighbor model is adequate for predicting thermodynamics of oligonucleotides with internal C.T with… CONTINUE READING

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