Thermodynamics and kinetics of protein incorporation into membranes.

  title={Thermodynamics and kinetics of protein incorporation into membranes.},
  author={Fritz J{\"a}hnig},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={80 12},
  • Fritz Jähnig
  • Published 1983 in
    Proceedings of the National Academy of Sciences…
The free energy and enthalpy of protein incorporation into membranes are calculated with special emphasis on the hitherto neglected effects of immobilization of protein and perturbation of lipid order in the membrane. The free energy change is found to be determined by the hydrophobic effect as the driving force for incorporation and the protein immobilization effect which leads to a considerable reduction of the free energy gained from the hydrophobic effect. For incorporation of a hydrophobic… CONTINUE READING

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