Thermodynamically based constraints for rate coefficients of large biochemical networks.

  title={Thermodynamically based constraints for rate coefficients of large biochemical networks.},
  author={Marcel O. Vlad and J. Ross},
  journal={Wiley interdisciplinary reviews. Systems biology and medicine},
  volume={1 3},
Wegscheider cyclicity conditions are relationships among the rate coefficients of a complex reaction network, which ensure the compatibility of kinetic equations with the conditions for thermodynamic equilibrium. The detailed balance at equilibrium, that is the equilibration of forward and backward rates for each elementary reaction, leads to compatibility between the conditions of kinetic and thermodynamic equilibrium. Therefore, Wegscheider cyclicity conditions can be derived by eliminating… CONTINUE READING

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