Thermodynamic dissociation constants of silychristin, silybin, silydianin and mycophenolate by the regression analysis of spectrophotometric data

@article{Meloun2003ThermodynamicDC,
  title={Thermodynamic dissociation constants of silychristin, silybin, silydianin and mycophenolate by the regression analysis of spectrophotometric data},
  author={Milan Meloun and Dominika Burkoňov{\'a} and Tom{\'a}s Syrov{\'y} and Ale{\vs} Vr{\'a}na},
  journal={Analytica Chimica Acta},
  year={2003},
  volume={486},
  pages={125-141}
}

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References

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Silybin, a new iron-chelating agent.
Effects of Silymarin MZ-80 on Hepatic Oxidative Stress in Rats with Biliary Obstruction
TLDR
All three derivatives of silymarin show a clear ability to reduce lipid peroxidation in the liver in rats with extrahepatic biliary obstruction and sham-operated animals.
Silymarin protects against paracetamol‐induced lipid peroxidation and liver damage
TLDR
It was concluded that silymarin can protect against APAP intoxication through its antioxidant properties, possibly acting as a free‐radical scavenger.
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