Thermodynamic aspects of cAMP dependent protein kinase catalytic subunit allostery.

Abstract

Kinetics of thermal inactivation of acrylodan-labeled cAMP dependent protein kinase catalytic subunit, its binary complexes with ATP and peptide inhibitor PKI[5-24], respectively, and the ternary complex involving both of these ligands were studied at different temperatures (5-50 °C). The thermodynamic parameters ΔH and ΔS for ligand binding equilibria as… (More)
DOI: 10.1007/s10930-014-9570-1

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Cite this paper

@article{Kivi2014ThermodynamicAO, title={Thermodynamic aspects of cAMP dependent protein kinase catalytic subunit allostery.}, author={Rait Kivi and Per Jemth and Jaak J{\"a}rv}, journal={The protein journal}, year={2014}, volume={33 4}, pages={386-93} }