Thermodynamic and kinetic characterization of the dissociation and assembly of quadruplex nucleic acids.

@article{Hardin2000ThermodynamicAK,
  title={Thermodynamic and kinetic characterization of the dissociation and assembly of quadruplex nucleic acids.},
  author={Charles Hardin and Alexander G. Perry and Katherine White},
  journal={Biopolymers},
  year={2000},
  volume={56 3},
  pages={147-94}
}
The dissociation and assembly of quadruplex DNA structures (and a few quadruplex RNAs) have been characterized at several levels of rigor, ranging from gross descriptions of factors that govern each process, to semiquantitative comparisons of the relative abilities of these factors to induce stabilization or destabilization, to quantitative studies of binding energies (thermodynamics), transformational rates (kinetics), and analysis of their transition-state energies and mechanisms. This survey… CONTINUE READING
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