Thermodynamic and Kinetic Insights into Stop Codon Recognition by Release Factor 1

@inproceedings{Trappl2014ThermodynamicAK,
  title={Thermodynamic and Kinetic Insights into Stop Codon Recognition by Release Factor 1},
  author={Krista Trappl and Merrill A. Mathew and Simpson Joseph},
  booktitle={PloS one},
  year={2014}
}
Stop codon recognition is a crucial event during translation termination and is performed by class I release factors (RF1 and RF2 in bacterial cells). Recent crystal structures showed that stop codon recognition is achieved mainly through a network of hydrogen bonds and stacking interactions between the stop codon and conserved residues in domain II of RF1… CONTINUE READING