Thermodynamic analysis of DNA binding by a Bacillus single stranded DNA binding protein

Abstract

Single-stranded DNA binding proteins (SSB) are essential for DNA replication, repair, and recombination in all organisms. SSB works in concert with a variety of DNA metabolizing enzymes such as DNA polymerase. We have cloned and purified SSB from Bacillus anthracis (SSBBA). In the absence of DNA, at concentrations ≤100 μg/ml, SSBBA did not form a stable… (More)
DOI: 10.1186/1471-2091-13-10

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