Thermochemical and kinetic evidence for nucleotide-sequence-dependent RecA-DNA interactions.

@article{Wittung1997ThermochemicalAK,
  title={Thermochemical and kinetic evidence for nucleotide-sequence-dependent RecA-DNA interactions.},
  author={Pernilla Wittung and Christine Ellouze and Fabrice Maraboeuf and Masayuki Takahashi and B. Nelson Norden},
  journal={European journal of biochemistry},
  year={1997},
  volume={245 3},
  pages={715-9}
}
RecA catalyses homologous recombination in Escherichia coli by promoting pairing of homologous DNA molecules after formation of a helical nucleoprotein filament with single-stranded DNA. The primary reaction of RecA with DNA is generally assumed to be unspecific. We show here, by direct measurement of the interaction enthalpy by means of isothermal… CONTINUE READING