Thermal stabilization of anti‐&agr;‐cobratoxin single domain antibodies

@article{Anderson2017ThermalSO,
  title={Thermal stabilization of anti‐&agr;‐cobratoxin single domain antibodies},
  author={George P. Anderson and J. H. Liu and Dan Zabetakis and Jinny L. Liu and Ellen R. Goldman},
  journal={Toxicon},
  year={2017},
  volume={129},
  pages={68–73}
}
Abstract There is an unmet need for snake antivenoms that can be stored ready to use near the point of care. To address that need we have taken two anti‐&agr;‐cobratoxin single domain antibodies and increased their thermal stability to improve their ambient temperature shelf‐life. The anti‐&agr;‐cobratoxin single domain antibodies C2 and C20 were first isolated, and demonstrated to be toxin neutralizing by Richard et al., 2013 (Richard, G., Meyers, A.J., McLean, M.D., Arbabi‐Ghahroudi, M… CONTINUE READING

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