Thermal scribing to prototype plastic microfluidic devices, applied to study the formation of neutrophil extracellular traps.

@article{Chandrasekaran2017ThermalST,
  title={Thermal scribing to prototype plastic microfluidic devices, applied to study the formation of neutrophil extracellular traps.},
  author={A. Chandrasekaran and Nikita Kalashnikov and Roni Rayes and Claire C Wang and Jonathan D. Spicer and Christopher Moraes},
  journal={Lab on a chip},
  year={2017},
  volume={17 11},
  pages={
          2003-2012
        }
}
Innovation in microfluidics-based biological research has been aided by the growing accessibility of versatile microscale fabrication techniques, particularly in rapid prototyping of elastomeric polydimethylsiloxane (PDMS) based devices. However, the use of PDMS presents considerable and often unexpected limitations, particularly in interpreting and validating biological data. To rapidly prototype microfluidic culture systems in conventional plastics commonly used in cell culture, we developed… CONTINUE READING