Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy.

@article{Thrall2005ThermalDI,
  title={Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy.},
  author={Donald E. Thrall and Susan M Larue and Daohai Yu and Thaddeus V. Samulski and Linda Sanders and Beth Case and Gary L. Rosner and Chieko Azuma and Jeannie Poulson and Amy F Pruitt and Wilma E Stanley and Marlene L. Hauck and Laurel Williams and Paul E. Hess and Mark W. Dewhirst},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2005},
  volume={11 14},
  pages={5206-14}
}
PURPOSE To test that prospective delivery of higher thermal dose is associated with longer tumor control duration. EXPERIMENTAL DESIGN 122 dogs with a heatable soft tissue sarcoma were randomized to receive a low (2-5 CEM43 degrees CT90) or high (20-50 CEM43 degrees CT90) thermal dose in combination with radiotherapy. Most dogs (90%) received four to six hyperthermia treatments over 5 weeks. RESULTS In the primary analysis, median (95% confidence interval) duration of local control in the… CONTINUE READING

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