Thermal copoly(amino acids) as inhibitors of glyoxalase I.

  title={Thermal copoly(amino acids) as inhibitors of glyoxalase I.},
  author={S. Fox and R. M. Syren and C. R. Windsor},
  journal={Ciba Foundation symposium},
A number of copoly(alpha-amino acids) have been prepared thermally; some have been found to function as inhibitors of glyoxalase I, an enzyme which occupies a central position in Szent-Györgyi's theory of tumour genesis. These polymers are also of interest in the search for synthetic peptides having carcinostatic activity, since many natural peptides are active. The way in which the inhibitory activity varies with composition of the synthetic polymers has been investigated. Various properties… Expand
2 Citations
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