Thermal behavior and stability of biodegradable spray-dried microparticles containing triamcinolone.

@article{Silva2009ThermalBA,
  title={Thermal behavior and stability of biodegradable spray-dried microparticles containing triamcinolone.},
  author={Arn{\'o}bio Ant{\^o}nio da Silva and Jivaldo Ros{\'a}rio de Matos and Thalita Pedroni Formariz and Gustavo Rossanezi and Maria Virg{\'i}nia Costa Scarpa and Eryvaldo S{\'o}crates Tabosa do Egito and Anselmo Gomes de Oliveira},
  journal={International journal of pharmaceutics},
  year={2009},
  volume={368 1-2},
  pages={
          45-55
        }
}
Thermal analysis has been widely used for obtaining information about drug-polymer interactions and for pre-formulation studies of pharmaceutical dosage forms. In this work, biodegradable microparticles of poly (d,L-lactide-co-glycolide) (PLGA) containing triamcinolone (TR) in various drug:polymer ratios were produced by spray drying. The main purpose of this study was to study the effect of the spray-drying process not only on the drug-polymer interactions but also on the stability of… CONTINUE READING
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