Thermal and chemical modification of titanium-aluminum-vanadium implant materials: effects on surface properties, glycoprotein adsorption, and MG63 cell attachment.

@article{Macdonald2004ThermalAC,
  title={Thermal and chemical modification of titanium-aluminum-vanadium implant materials: effects on surface properties, glycoprotein adsorption, and MG63 cell attachment.},
  author={D E Macdonald and Bruce E. Rapuano and Namita Deo and Mike Stranick and P. Somasundaran and Adele Ludin Boskey},
  journal={Biomaterials},
  year={2004},
  volume={25 16},
  pages={3135-46}
}
The microstructure, chemical composition and wettability of thermally and chemically modified Ti-6Al-4V alloy disks were characterized and correlated with the degree of radiolabeled fibronectin-alloy surface adsorption and subsequent adhesion of osteoblast-like cells. Heating either in pure oxygen or atmosphere (atm) resulted in an enrichment of Al and V within the surface oxide. Heating (oxygen/atm) and peroxide treatment both followed by butanol treatment resulted in a reduction in content of… CONTINUE READING