Therapy-related acute promyelocytic leukemia: a systematic review.

  title={Therapy-related acute promyelocytic leukemia: a systematic review.},
  author={Armin Rashidi and Stephen I. Fisher},
  journal={Medical oncology},
  volume={30 3},
The incidence of therapy-related acute promyelocytic leukemia (t-APL) is apparently rising. We systematically reviewed the English literature until March 15, 2013, and collected a total of 326 t-APL cases, with the following results: (1) t-APL affects predominantly middle-aged adults with a median age at diagnosis of 47 years and a female-to-male ratio of 1.7:1; (2) after an incidence peak at 2 years following the completion of treatment for the primary antecedent disease, the risk of… CONTINUE READING


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