Therapy of steroid-resistant inflammatory bowel disease.

@article{Manz2012TherapyOS,
  title={Therapy of steroid-resistant inflammatory bowel disease.},
  author={Michael Manz and Stephan R. Vavricka and Roger M Wanner and Peter L Lakatos and Gerhard Rogler and Pascal Frei and Ekaterina Safroneeva and Alain M. Schoepfer},
  journal={Digestion},
  year={2012},
  volume={86 Suppl 1},
  pages={11-5}
}
BACKGROUND AND AIMS Although systemic corticosteroids are successfully administered for the induction of clinical response and remission in the majority of patients with inflammatory bowel disease (IBD) presenting with a flare, a proportion of these patients demonstrate a primary nonresponse to steroids or in the case of an initial response, they develop a resistance or a steroid dependence. Long-term therapy with corticosteroids for treatment of IBD should be avoided, given the high frequency… CONTINUE READING

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