Therapy of interferon-induced depression in chronic hepatitis C with citalopram: a randomised, double-blind, placebo-controlled study

@article{Kraus2007TherapyOI,
  title={Therapy of interferon-induced depression in chronic hepatitis C with citalopram: a randomised, double-blind, placebo-controlled study},
  author={M. Kraus and A. Sch{\"a}fer and K. Sch{\"o}ttker and C. Keicher and B. Weissbrich and I. Hofbauer and M. Scheurlen},
  journal={Gut},
  year={2007},
  volume={57},
  pages={531 - 536}
}
  • M. Kraus, A. Schäfer, +4 authors M. Scheurlen
  • Published 2007
  • Medicine
  • Gut
  • Background: Interferon-induced depression represents a major complication in antiviral treatment of chronic hepatitis C virus (HCV) infection. Aim: To evaluate in a placebo-controlled study the efficacy of a selective serotonin reuptake inhibitor (SSRI) in HCV patients on antiviral therapy with interferon-associated depression. Methods: 100 HCV outpatients were included in a randomised, double-blind, placebo-controlled study. During interferon therapy (peginterferon alfa-2b plus ribavirin… CONTINUE READING
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