Therapy of complex I deficiency: Peripheral neuropathy during dichloroacetate therapy


A therapeutic trial with polyvitamins and dichloroacetate (DCA) in combination with thiamine in a 13-year-old girl with complex I deficiency is reported. The polyvitamin therapy included thiamine, riboflavin, ascorbate, coenzyme Q 10 and carnitine. This therapeutic regine was used over a period of 17 months without any effect. Although DCA lowered the… (More)
DOI: 10.1007/BF01957508

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