Therapy and prophylaxis of brain metastases.

  title={Therapy and prophylaxis of brain metastases.},
  author={Yvonne Kienast and Frank Winkler},
  journal={Expert review of anticancer therapy},
  volume={10 11},
Metastases of various tumors to the brain account for the majority of brain cancers, and are associated with a poor prognosis. The most common primary sites are lung, breast, skin, kidney and colon; 10-40% of cancer patients develop brain metastases during the course of the disease. The incidence of brain metastasis appears to be rising; reasons may include better therapies for the systemic disease with longer survival of cancer patients but lower efficiency against brain metastases. In this… CONTINUE READING


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