Therapie und Prävention der Hyperthyreose

  title={Therapie und Pr{\"a}vention der Hyperthyreose},
  author={U. Woenckhaus and C. Girlich},
  journal={Der Internist},
ZusammenfassungTSH-Werte unterhalb des Referenzbereichs werden in Deutschland bei über 10% der Bevölkerung beobachtet. Nicht immer handelt es sich um therapiebedürftige Hyperthyreosen. Insbesondere bei älteren Patienten kann sich hierunter aber eine Schilddrüsenautonomie verbergen, die durch iatrogene Jodzufuhr zu schwer beherrschbaren Entgleisungen führen kann. Prophylaktisch und therapeutisch bietet sich neben den Thionamiden der Einsatz von Perchlorat an. Mittelfristig ist eine definitive… Expand
1 Citations
The prevalence of undiagnosed thyroid disorders in a previously iodine-deficient area.
There are a number of thyroid Disorders in this previously iodine-deficient region and further studies are required to investigate the change of thyroid disorders during iodine supplementation programs. Expand


Leitlinie zur Radioiodtherapie bei benignen Schilddrüsenerkrankungen (Version 3)
Die Version 3 der Leitlinie zur Radioiodtherapie (RIT) bei benignen Schilddrusenerkrankungen stellt im Wesentlichen eine redaktionelle Uberarbeitung der Version 2 dar. Im Kapitel Indikation undExpand
Review of antithyroid drug use during pregnancy and report of a case of aplasia cutis.
It is concluded that there is insufficient evidence either to establish or eliminate a direct causal relationship between ACC and MMI use, and propylthiouracil is the preferred thioamide for hyperthyroidism during pregnancy. Expand
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It is demonstrated that levothyroxine does not prevent relapse of hyperthyroidism after successful restoration of euthyroid function by antithyroid drugs and characterizes posttreatment TSH as a main prognostic marker. Expand
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In euthyroid unselected patients from an iodine-deficient area short-term iodine contamination by contrast media rarely leads to hyperthyroidism, and prophylactic therapy is not generally recommended. Expand
Levels of autoantibodies against human TSH receptor predict relapse of hyperthyroidism in Graves' disease.
The data clearly indicate that TRAb measurement is useful for identifying patients that will not benefit from long-term antithyroid drug treatment. Expand
Effects of Carnitine on Thyroid Hormone Action
It is shown that 2 and 4 grams per day of oral l‐carnitine are capable of reversing hyperthyroid symptoms (and biochemical changes in the hyper thyroidroid direction) as well as preventing (or minimizing) the appearance of hyperthy thyroid hormone symptoms (or biochemicalChanges in thehyperthyroid direction). Expand
A prospective randomized trial of antithyroid drug dose in Graves' disease therapy. European Multicenter Study Group on Antithyroid Drug Treatment.
It does not appear justified at present to recommend MMI doses higher than required for the control of hyperthyroidism (with the goal of immunosuppression), and under conditions of iodine deficiency or borderline sufficient iodine supply, 40 mg MMI daily will render more patients with Graves' disease euthyroid within the first 6 weeks of treatment than 10 mg daily, but at the expense of an increased rate of adverse reactions. Expand
Selenium in the treatment of autoimmune thyroiditis
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In patients with low levels of TSH, the risk of hyperthyroidism after application of iodine-containing contrast media is negligible if TCTU is less than 1%. Expand
Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
It is concluded that selenium substitution may improve the inflammatory activity in patients with autoimmune thyroiditis, especially in those with high activity. Expand