Therapeutics targeting the innate immune system

@article{Ulevitch2004TherapeuticsTT,
  title={Therapeutics targeting the innate immune system},
  author={Richard J Ulevitch},
  journal={Nature Reviews Immunology},
  year={2004},
  volume={4},
  pages={512-520}
}
Proteins that recognize the components and products of microorganisms have an important role in innate immunity. Here, I focus on recent advances in our understanding of the function of several such protein families. In particular, I consider how members of the TLR (Toll-like receptor), NOD (nucleotide-binding oligomerization domain)-protein and MyD88 (myeloid differentiation primary-response protein 88) families are providing emerging opportunities for the development of new therapeutics that… CONTINUE READING

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