Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
@article{Muhammad2017TherapeuticUO, title={Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.}, author={Zehra Abdul Muhammad and Tashfeen Ahmad}, journal={JPMA. The Journal of the Pakistan Medical Association}, year={2017}, volume={67 1}, pages={ 121-125 } }
Bromelain is an extract obtained from the pineapple plant and is used as a traditional folk remedy for several ailments. In this review, a comprehensive electronic database search was carried out to compile available literature on therapeutic implications of bromelain. Pharmaceutical value of bromelain has been demonstrated in different surgical sub-specialties. Diverse biological processes like anti-inflammatory, anti-oedematous, analgesic, anti-thrombotic, exfoliation etc. are involved in…
32 Citations
Recent Advances and Insights into Bromelain Processing, Pharmacokinetics and Therapeutic Uses
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- 2021
The state of the art in the main conventional and unconventional extraction and purification methods of bromelain are described and the advantages and limitations of these strategies are discussed.
In vitro performance of free and encapsulated bromelain
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- 2021
N nanoencapsulation of bromelain with chitosan conferred physical protection, delayed release, and wound retraction activity to the formulation, properties that favor topical formulations with a modified release.
Enhancement of the Anti-inflammatory Effect of Bromelain by Its Immobilization on Probiotic Spore of Bacillus cereus
- BiologyProbiotics and Antimicrobial Proteins
- 2020
The results showed that used alone, the enzyme and the spores produced oedema inhibition and improved the motility of the rats, and the spore-immobilized bromelain formulation performed approximately 0.9-fold better than the free bromalain and the free spores at the lower evaluated dose.
A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study
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- 2023
The preliminary data suggest that the addition of supplement containing Ribes nigrum, Boswellia serrata, Vitamin D and Bromelain to the traditional local therapy (nasal spray with cortisone) can be a supporting therapy to modulate the local inflammation in the nose in patients affected by chronic sinusitis.
Effect of 20% ethanol extract of Subang pineapple gel on oral mucosa incisional wound length
- MedicinePadjadjaran Journal of Dentistry
- 2022
Topical application of pineapple extract affected oral mucosa incisional wound healing and had a potential to accelerate wound closure.
New Mechanisms of Bromelain in Alleviating Non-Alcoholic Fatty Liver Disease-Induced Deregulation of Blood Coagulation
- Biology, MedicineNutrients
- 2022
Findings suggest that bromelain exerts anticoagulant effects on NAFLD-induced deregulation of coagulation by inhibiting the activation of the coagulations cascade, decreasing the stability of clots, and promoting fibrinolytic activity.
Debridement Applications of Bromelain: A Complex of Cysteine Proteases from Pineapple
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- 2017
There are many types of proteases in the nature, since they represent about 2% of protein coding genes and plants are excellent sources of proteolytic enzymes with great activity and stability, and Therapeutic enzymes are the major biopharmaceuticals.
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Traditional used natural actives for wound healing are reviewed, highlighting their characteristics and mode of action and how they can be used for cutaneous wound treatment.
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Results seem to indicate an interference of bromelain with arachidonic acid cascade, which deserves further investigation to be better assessed.